Most columns are easy to understand. These are some particular columns:
gwas_class: A class of GWAS used to define pleiotropy in our manuscript.
pp_h4_abf: The probability of the window to share the same causal variant of the expression and GWAS phenotype.
snp_pp_h4: The probability of the SNP being causal given that the Hypothesis H4 is true.
tophits_variant_id: The reference variant for the 100,000 bp window used for the colocalization.
nspns: Then number of SNPs included in the colocalization 100,000 bp window.
What's new
2022-12-14
Version 0.1.3 of the colocalization database with 127 eQTL biosamples, 293 GWAS, 138,274 included
variants and 8,824,741 combinations of variant, eQTL gene and GWAS.
If you use this resource, please cite our publication: Pleiotropic expression quantitative trait loci are enriched in enhancers and transcription factor binding sites and impact more genes. Aitor González, Pascale Paul. Comput Struct Biotechnol J. 2024 Nov 17:23:4260-4270. doi: 10.1016/j.csbj.2024.11.019.